Nanodevice and Nanobioengineering Research

General Research Directives

Diagram

Nanodevice Research

The application of nanotechnology to the field of medicine has tremendous promise for increasing our ability to diagnose, image, and treat disease. The efforts of this investigational group are centered on developing "lab-on-a-chip" devices which can be used for analyzing blood and other biological samples. We are also very interested in developing new types of particles that can be used for drug delivery and imaging of the human body. These latter devices will be made up of nano-MEMS chips, nanopatterens and nanostructured materials.

Nanobioengineering

Nanobioengineering is a young and rapidly evolving field of research at the cross roads of biotechnology and nanoscience that is considered one of the key technologies of the 21st century. A long term goal of nanobiotechnology is the utilization of biomolecular motors for controlled cargo manipulation on a chip, with applications in sorting, separation, purification or assembly of materials. Recent work in our laboratory and elsewhere has clearly demonstrated that biomolecular motors can be used to transport molecular cargo across a micropatterned surface and that we can exert varying degrees of control over their motion. Our current activities within this area of inquiry are directed towards increasing our ability to:

  1. Direct and monitor cargo travel
  2. Regulate cargo loading and unloading
Cartoon depicting construction of actin bundles
Actin bundle loaded with molecular cargo
Action Bundle
Images of actin bundle unloading molecular cargo.