Translational Genomic Research Institute

Donald Primerano, Ph.D.The Charles H. McKown, Jr., MD, Translational Genomic Research Institute (TGRI) occupies 10,500 square feet on the third floor of the Edwards Cancer Care Center at Cabell Huntington Hospital. The TGRI supports the Joan C. Edwards school’s basic science offerings and clinical researchers by enabling them to rapidly translate genome-based laboratory research into clinical applications that will improve patient care.

The institute’s primary goal is to enable Marshall researchers to conduct a greater number of investigator-initiated clinical trials. Allowing basic scientists to work in close proximity to clinicians will encourage them to collaborate, providing new research ideas and clinical applications. The professors currently researching at the TGRI include Dr. Pier Paolo Claudio, Dr. W. Elaine Hardman, and Dr. Niles.

The TGRI is also the home of the West Virginia Cancer Genomics Network, which includes two members: Marshall University and the Mary Babb Randolph Cancer Center at West Virginia University. The network seeks to develop a database of genomic information that will allow researchers to compare the genes of multiple patients suffering from the same types of cancer. The network hopes to help enable doctors and researchers to predict patient response to targeted therapies, and to help identify whether patients at risk of developing a condition express the same mutations as patients with full-blown cancer.

M. Allison Wolf, Ph.D. candidateAnyone interested in learning more about the TGRI or in contributing to its operations can contact Dr. Niles directly at Biomedical Sciences graduate students and medical and postdoctoral students who are interested in working at the institute may submit their résumés to