Rounak P. Nande successfully defended his dissertation: Investigation of ultrasound -targeted microbubbles as a therapeutic gene delivery system for prostate cancer. Nande’s research in the laboratory of Pier Paulo Claudio, M.D./Ph.D., focused on utilizing these microbubbles to carry adenoviral vectors with therapeutic genes to a cancerous tumor site. This delivery is shielded from discovery and quick deterioration by the immune system. According to Rounak, “this is particularly important in cancer gene therapy for potentially inaccessible tumors because the microbubbles may also limit the amount of inflammatory response to the viruses and may allow repeated injections. Thus, our novel viral delivery technique mediated by microbubbles and ultrasound brings new hope to the frontier of gene therapy and its use in clinical settings.”
Rounak has presented several posters of his research at different conferences in the USA such as American Society of Gene and Cell Therapy (ASGCT), Star Symposium, Center for Clinical and Translational Science (CCTS), Experimental Biology Conference (EB), Annual Research Day at the school of medicine, and the Appalachian Regional Cell Conference (ARCC). Also, he has presented orally at the annual research day for four consecutive years. Rounak’s “accolades include receiving a travel award from Marshall University for the Experimental Biology Conference, and a paid trip to an international meeting for winning the Best Overall Performance as a Graduate Student award in 2014. Additionally, since ARCC’s inception, Rounak has won 1st or 2nd place in poster competition for every ARCC conference entered. Lastly, he has received the NASA West Virginia space grant in the years 2013-2014 and 2014-2015,” said Dr. Pier Paulo Claudio, Nande’s mentor. Claudio also stated that Nande’s research has resulted in two publications – a first author and a second author – in addition to a book chapter in Cutting Edge Therapies for Cancer in the 21st Century.
Congratulations on your graduation, Rounak Nande, Ph.D.!