The Material Safety Data Sheet (MSDS) is used to communicate chemical hazard information from the manufacturer to the employee. This is the information needed to inform and train employees on the safe use of hazardous chemicals. We are required to have an MSDS for each hazardous chemical product we use and keep paper copies in the safety room. The MSDS form Let's look at the MSDS form, itself. Some of the terms in each section link to additional information. You can check out the glossary at the end for general information on terms you may not be familiar with. Important points related to each MSDS section will be shown and then an example that illustrates those points will be shown. So, let's start the review. Each material safety data sheet must be in English (although the employer may maintain copies in other languages as well), and must contain at least the following information:
SUBSTANCE: **BENZOIC ACID** TRADE NAMES/SYNONYMS: BENZENECARBOXYLIC ACID; CARBOXYBENZENE; DRACYLIC ACID; PHENYL CARBOXYLIC ACID; PHENYLFORMIC ACID; RETARDER BA; TENN-PLAS; RETARDEX; SOLVO POWDER; SALVO LIQUID; PHENYLCARBOXYLIC ACID; BENZOATE; BENZENEMETHANOIC ACID; BENZENEFORMIC ACID; STCC 4966340; A-63; A-65; A-68; BP344; C7H6O2; ACC02720 CHEMICAL FAMILY: Carboxylic acid, aromatic MOLECULAR FORMULA: C6-H5-C-O2-H
MOLECULAR WEIGHT: 122.12
CERCLA RATINGS (SCALE 0-3): HEALTH=3 FIRE=1 REACTIVITY=0 PERSISTENCE=2 NFPA RATINGS (SCALE 0-4): HEALTH=2 FIRE=1 REACTIVITY=U
5000 pounds CERCLA Section 103 Reportable Quantity
BOILING POINT: 480 F (249 C)
MELTING POINT: 252 F (122 C)
SPECIFIC GRAVITY: 1.2659 @ 15 C
VAPOR PRESSURE: 1 mmHg @ 205 F
PH: 2.8 (satd solution)
SOLUBILITY IN WATER: 2.9% @ 20 C
VAPOR DENSITY: 4.2
SOLVENT SOLUBILITY: Soluble in alcohol, ether, benzene, chloroform, acetone, carbon disulfide, oil of turpentine, carbon tetrachloride, fixed and volatile oils; slightly soluble in petroleum ether, hexane.
LOWER EXPLOSIVE LIMIT: 3 g/ft3
AUTOIGNITION TEMPERATURE: 1060 F (571 C)
FIREFIGHTING MEDIA: Dry chemical, carbon dioxide, water spray or regular foam (1990 Emergency Response Guidebook, DOT P 5800.5). For larger fires, use water spray, fog or regular foam (1990 Emergency Response Guidebook, DOT P 5800.5). FIREFIGHTING: Move container from fire area if you can do it without risk. Do not scatter spilled material with high-pressure water streams. Dike fire-control water for later disposal (1990 Emergency Response Guidebook, DOT P 5800.5, Guide Page 31). Use water in flooding quantities as a fog; solid streams of water may be ineffective. Cool affected containers with flooding quantities of water applying water from as far a distance as possible. Avoid breathing vapors or dusts.
INCOMPATIBILITIES: OXIDIZERS (STRONG): Vigorous exothermic reaction.
DECOMPOSITION: Thermal decomposition products may include toxic oxides of carbon.
POLYMERIZATION: Hazardous polymerization has not been reported to occur under normal temperatures and pressures.
LOCAL EFFECTS: Irritant- eye.
ACUTE TOXICITY LEVEL: Moderately toxic by ingestion.
TARGET EFFECTS: Poisoning may affect the respiratory and central nervous system.
CREATION DATE: 11/02/84
REVISION DATE: 12/23/93 ADDITIONAL INFORMATION - THE INFORMATION BELOW IS BELIEVED TO BE ACCURATE AND REPRESENTS THE BEST INFORMATION CURRENTLY AVAILABLE TO US. HOWEVER, WE MAKE NO WARRANTY OF MERCHANTABILITY OR ANY OTHER WARRANTY, EXPRESS OR IMPLIED, WITH RESPECT TO SUCH INFORMATION, AND WE ASSUME NO LIABILITY RESULTING FROM ITS USE. USERS SHOULD MAKE THEIR OWN INVESTIGATIONS TO DETERMINE THE SUITABILITY OF THE INFORMATION FOR THEIR PARTICULAR PURPOSES.
Employers must maintain in the workplace copies of the required material safety data sheets for each hazardous chemical, and must ensure that they are readily accessible to employees when they are in their work area(s). (Electronic access, microfiche, and other alternatives to maintaining paper copies of the material safety data sheets are permitted as long as no barriers to immediate employee access in each workplace are created by such options.) Marshall recommends using the internet to find the necessary MSDS sheets if they are not provided in the folder of MSDSs in the lab.
However, the employer must ensure that in all cases the required information is provided for each hazardous chemical, and is readily accessible during each work to employees when they are in in their work area(s). Usually, MSDSs will be kept at the "Right to Know" station in a centralized location where most of the work is being accomplished. Along with the MSDSs, there must be a list of chemicals with an effective reference system to help the employee quickly locate a specific MSDS.
Finally, on the next page is a form for you to print out and sign signifying that you have read these modules and agree to follow the rules. You are to turn this form into the lab instructor. The chemistry department will be conducting random inspections of the labs. If it is discovered that the lab is in an unacceptable condition, the last TA to have used the lab will be required to rectify the situation.
GLOSSARY OF TERMSAcute Exposure - a short-term exposure usually occurring at high concentration. Back
Acute Health Effect - an effect that develops either immediately or a short time after exposure.
Antidote - a remedy or other agent to counteract the effects of a poison. Back
Atomic Weight - The average weight of an atom of an element, usually expressed relative to one atom of the carbon isotope taken as a weight of 12. Back
Autoignition Temperature - the minimum temperature required to initiate or cause self-sustained combustion, in the absence of a spark or flame. Back
Biohazardous Infectious Material - a material that contains organisms and the toxins produced by these organisms that have been shown to cause disease or are believed to cause disease in either humans or animals.
Boiling Point - the temperature at which a liquid changes from a liquids to a gas, at normal atmospheric pressure. Back
Carcinogens - agents/compounds that may induce cancer in humans. Back
CAS Registry Number - a number assigned to a material by the Chemical Abstracts Service (CAS) to provide a single unique identifier. Back
Chemical Formula - sometimes called the molecular formula, indicates the elements that make up a chemical.
Chemical Name - a proper scientific name for the active ingredient of a product.
Chronic Exposure - a long-term exposure, usually occurring at low concentrations. Back
Chronic Health Effects - an effect that appears a long time after exposure.
Coefficient of Oil/Water Distribution - the ratio of the solubility of the chemical in an oil to its solubility in water.
Combustible Liquid - a liquid which has a flash point above 37.8 C.
Compressed Gas - a material which is a gas at normal room temperature (20 C) and pressure but is packaged as a pressurized gas, dissolved gas or gas liquefied by compression or refrigeration.
Condensation - the process of reducing from one form to another denser form such as steam to water.
Controlled Products - Under the Controlled Products Regulation, a controlled product is defined as a material, product or substance which is imported or sold in Canada and meets the criteria for one or more of the following classes: -
Corrosive Material - a material that can attack (corrode) metals or cause permanent damage to human tissues such as skin and eyes on contact.
Cryogenics - materials which exist at extremely low temperatures, such as liquid nitrogen.
Dangerously Reactive Materials - materials that may undergo vigorous condensation, decomposition or polymerization. They may react violently under conditions of shock or increase in pressure or temperature. They may also react vigorously with water or water vapor to release a toxic gas.
Decomposition - the breakdown of a substance, often due to heat, decay or other effect, with the release of other compounds such as vapors or gases that may be flammable or toxic.
Density - the weight of a material in a given volume. It is usually given in grams per millilitre (g/ml).
Dilution Ventilation - dilution of contaminated air with uncontaminated air in a general area, room or building for the purposes of health hazard or nuisance control, and/or for heating and cooling.
Dose - amount of the agent that has entered the body through the various routes of entry.
Evaporation Rate - the rate at which a liquid changes to vapor at normal room temperature.
Explosive (Flammable) Limits - the lower explosive (flammable) limit (LEL) is the lowest concentration of vapor in air which will burn or explode upon contact with a source of ignition. The upper explosive (flammable) limit (UEL) is the highest concentration of vapor in air which will burn or explode upon contact with a source of ignition. Back
Explosive (Flammable) Range - the range between the lower explosive limit (LEL) and the upper explosive limit (UEL).
Exposure Limits- established concentrations which, if not exceeded, will not generally cause adverse effects to the worker exposed. Exposure limits differ in name and meaning depending on origin. For example:-
TWAEV Time-Weighted Average Exposure Value: The average airborne concentration of a biological or chemical agent to which a worker may be exposed in a work day or a work week.
STEV Short Term Exposure Value: - The maximum airborne concentration of a chemical or biological agent to which a worker may be exposed in any 15 minute period, provided the TWAEV is not exceeded.
CEV Ceiling Exposure Value: The maximum airborne concentration of a biological or chemical agent to which a worker may be exposed at any time.
SKIN: This notation indicates that direct or airborne contact with the product may result in significant absorption of the product through the skin, mucous membranes or eyes. Inclusion of this notation is intended to suggest that preventative action be taken against absorption of the agent through these routes of entry.
TLV-TWA Threshold Limit Value - Time-Weighted Average: The time-weighted average concentration for a normal 8 hour work day and a 40 hour work week, to which nearly all workers may be repeatedly exposed, day after day, without adverse effect.
TLV-STEL Threshold Limit Value - Short Term Exposure Limit: a 15 minute time-weighted average exposure which should not be exceeded at any time during a work day even if the 8 hr TWA is within the TLV. Exposures at the STEL should not be repeated more than 4 times a day and there should be at least 60 minutes between successive exposures at the STEL.
TLV-C Threshold Limit Value - Ceiling: the concentration that should not be exceeded during any part of the working exposure.
Other exposure limits include the Permissible Exposure Limits (PEL) which are legal exposure limits in the United States.
Flammable Limits - "See Explosive Limits".
Flammable Substance - one that will readily catch fire and continue to burn in air if exposed to a source of ignition.
Flashback - this occurs when a trail of flammable material is ignited by a distant source of ignition. The flame then travels back along the trail of gas, vapor or aerosol to its source.
Flashpoint - the lowest temperature of a liquid at which it gives off enough vapor to form an ignitable mixture of vapor and air immediately above the liquid surface. Back
Freezing Point - the temperature at which a liquid becomes a solid, at normal atmospheric pressure.
Hazard- the potential for harmful effects.
Hazardous Combustion Products - chemicals which may be formed when a material burns. These chemicals may be flammable, toxic or have other hazards.
Hazardous Decomposition Products - formed when a material decomposes (breaks down) because it is unstable, or reacts with materials such as water or oxygen in air.
Hazardous Ingredient - Under the Hazardous Products Act, a chemical must be listed in the Hazardous Ingredients section of a MSDS if:-
Hazardous Polymerization - Polymerization is a process of forming a polymer by combining large numbers of chemical units or monomers into long chains (polyethylene from ethylene or polystyrene from styrene). Uncontrolled polymerization can be extremely hazardous. Some polymerization processes can release considerable heat or can be explosive.
Ingestion - means taking a material into the body by mouth (swallowing).
Inhalation - means taking a material into the body by breathing it in.
Irritant - some sort of aggravation of whatever tissue the material comes in contact with.
LC50 - the concentration of a material in air which causes death in 50% of a group of test animals. The material is inhaled over a set period of time, usually 4 hrs. LC stands for lethal concentration.
LD50 - the weight of material which causes the death in 50% of a group of test animals. It is usually expressed in weight of material per weight of test animal. LD stands for lethal dose.
LEL (Lower Explosive Limit) - See "Explosive Limits".
Local Exhaust Ventilation - involves the capture of pollutants at the source.
Material Causing Immediate and Serious Toxic Effects - classified under "Poisonous and Infectious Material" as toxic or very toxic based on information such as the LD50 or LC50.
Material Causing Other Toxic Effects - classified under "Poisonous and Infectious Material" as a material causing toxic effects such as skin or respiratory sensitization, carcinogenicity, mutagenicity, etc.
Melting Point - the temperature at which a solid material becomes a liquid. Back
Molecular Formula - A chemical formula that shows the number of atoms of each element in a molecule of a compound. Back
Molecular Weight - the sum of the atomic weights of a molecule's constituent atoms. Back
Mutagen - an agent that affects the genes or cells of the exposed people in such a way that it may cause cancer in the exposed individual or an undesirable mutation to occur in some later generation.
NA Number - See "UN number".
Odor Threshold - the airborne concentration, usually in part per million, at which an odor becomes noticeable.
Oxidizing Material - gives up oxygen easily or can readily oxidize other materials. Back
Permissible Exposure Limits (PEL) - legal limits in the U.S.A. set by the Occupational Safety and Health Administration (OSHA).
pH - a measure of the acidity or basicity (alkalinity) of a material when dissolved in water.
Polymer - a natural or man-made material formed by combining units, called monomers, into long chains.
Polymerization - a process of forming a polymer by combining large numbers of chemical units or monomers into long chains. Back
Parts Per Million (ppm) - represents the concentration of gases or vapor in air. For example, 1 ppm of a gas means that 1 unit of the gas is present for every 1 million units of air.Reactivity - tendency to participate in chemical reactions. Back
Sensitization - the development, over time, of an allergic reaction to a chemical.
Solubility - the ability of a material to dissolve in water or another liquid. Back
Solvent - a material which is capable of dissolving another chemical.
Specific Gravity - the density of a liquid compared to the density of an equal amount of water. Back
Stability - the ability of a material to remain unchanged in the presence of heat, moisture or air.
Teratogen - agents or compounds that a pregnant woman takes into her body that generate defects in the fetus.
TLV - See "exposure Limits".
Toxicity - ability of a substance to cause harmful effects. Back
Trade Name - the name under which a product is commercially known.
TWA - See "Exposure Limits".
UEL (Upper Explosive Limits) - See "Explosive Limits".
UN Number - a four digit number assigned to a potentially hazardous material or class of materials. UN (United Nations) numbers are internationally recognized and are used by fire fighter and other emergency response personnel for identification of materials during transportation emergencies. NA (North American) numbers are assigned by Transport Canada and the US Department of Transport to materials they consider hazardous and to which a UN number has not been assigned.
Vapor - a gaseous form of a material which is normally solid or liquid at room temperature and pressure.
Vapor Density - the density of a vapor compared to the density of an equal amount of air. Back
Vapor Pressure - the pressure of a vapor in equilibrium with its liquid or solid form. Back
Ventilation - the movement of air.
Volatility - the ability of a material to evaporate.