Marshall University Mathematics Colloquium
Friday, November 19, 3:00 P.M.
Smith Hall 509
Topological
Proteomics:
Pure
Mathematics in Life Sciences
Abstract: How can the 3-dimensional ‘folded’ structure of a protein be determined from the amino acid sequence? How can the function of a protein be determined from the 3-dimensional ‘folded’ structure? Concentrating mostly on the second question we apply techniques of algebraic topology to identify significant geometric features of the molecule. In this preliminary report we describe how we have been able to detect "tunnels" and "hands" normally used for holding a strand of DNA. A review of the necessary background material will be provided.
Snacks will be served.
Next Colloquium: Spring 2005.