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The responsible Institutional Official for all institutions affiliated with the Marshall University IRBs is the vice president for research. He/she is responsible for ensuring the independence of each IRB, its support and its standing within the institution. He/she has the responsibility for the implementation and operation of the Human Research Protection Program. The director/staff of the Office of Research Integrity assist in the day-to-day operations of the program.

The Institutional Official is authorized to review and sign a Department of Defense Addendum.