Research Terms/Definitions – A
AAALAC: Association for Assessment and Accreditation of Laboratory Animal Care, International – A private, nonprofit organization that promotes the humane treatment of animals in science through a voluntary accreditation program. It is the accrediting body for animal research programs recognized by the VA for VA animal research. www.aaalac.org
AAHRPP: The Association for the Accreditation of Human Research Protection Programs – The organization that the Department of Veterans Affairs has contracted with to provide its accreditation program for all VAMC human research protection programs. The purpose of the program is to strengthen the protections afforded to human subjects participating in research at a VAMC through an ongoing independent, external review. The program has been in place since 2/26/2002. www.aahrpp.org
AAMC: Association of American Medical Colleges – An organization whose mission is to improve the health of the public by enhancing the effectiveness of academic medicine. They support institutions, organizations and individuals associated with academic medicine in:
- Educating the physician and the medical scientist workforce;
- Discovering new medical knowledge;
- Developing innovative technologies for prevention, diagnosis
and treatment of disease;
- Providing health care services in academic settings.
Adverse Event (AE): Any reaction or undesirable event that occurs in conjunction with the use of a drug, biologic product, diagnostic agent, medical device, experimental procedure, or even accepted medical treatment (if part of a research protocol), whether or not the event is considered related to the drug treatment or procedures. Such events may be psychological, emotional, social and/or physical and include any illness, sign, symptom, or clinically significant laboratory test abnormality that has appeared or worsened during the course of the experimental study regardless of causal relationship to the drugs and procedures under study.
ARENA: Applied Research Ethics National Association – A national service organization for professionals concerned with issues relating to the protection of human subjects, the humane care and treatment of animals, scientific misconduct, ethical decision-making in healthcare, and other ethical issues pertaining to biomedical and behavioral research. Its mission is the promotion of networking among its members, the development of educational activities, the resolution and/or amelioration of mutual problems, and the professional advancement of its members in order to enhance the ethical conduct of research and medicine. www.primr.org
Assent: A child’s affirmative agreement to participate in research. Mere failure to object should not, absent affirmative agreement, be construed as assent.