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Name: Elizabeth Murray
Title: Associate Professor
Office: Integrated Science & Technology/COS
Phone: 304-696-2366
Expert: Ricin; Plant biotechnology; Recombinant DNA; Biotechnology manufacturing, Research and development and Quality assurance; Strawberry hydroponics; RNA and DNA purification

Research Based:
Funded Projects:
·“Transgenic Plants and RIPS”
Agency: Marshall University NASA WV Space Grant Consortium 12/1/1999-12/1/2000 ($8000).

·“Gene Expression in Hydroponically Grown Arabidopsis and Strawberry”
Agency: WV Space Grant Consortium Special Project. 7/1/2000-5/1/2001 ($8000)

·“Equipment to Enhance Research Capability in Plant Gene Transfer”
Agency: National Research Initiative Competitive Grants Program funded 9/1/2000- 9/1/2001 2001 ($17,000).

·"Evaluation of Strawberry as a Candidate Crop for Advanced Life Support"
Agency: WV Space Grant Consortium funded May 2001-May 2002 ($20,000)

·“Identification of Novel Ribosome Inactivating Proteins”
Agency: WV EPSCoR NSF Minigrant June 1-July 1, 2001($4000)

·“Flow cytometer acquisition”
Agency: NSF. Funded ($147,498) (PI: L. Jenski; Co-PI’s: S. Jackman, N. LoCascio, M. Harrison, E. Murray, and C. Somerville).

·“Gene mutation to demonstrate molecular techniques. NASA Space Grant Consortium K-12 Implementation Grant: 2001.”($1200) (PI: M. Harrison, Co-PI’s: N. LoCascio and E. Murray)

·"WV Biomedical Research Infrastructure Network" NIH ($3,884,371) 09/01/2001 – 08/31/2003. I am one of two co-directors for training and mentoring.

·Summer Research Grant 2002 Marshall University ($2000)

·"NCIIA E-Team Grant" , The Lemelson Foundation ($21,180) 08/01/2002 – 06/30/2003
Presentations Since 1999:
“Evaluation of Strawberry as a Candidate Crop for Advanced Life Support” American Society for Gravitational and Space Biology 17th Annual meeting November 7-10, 2001, Alexandria, VA. Poster session: November 9, 2001.

· Marshall University Sigma Xi Presentations with students: April 25-26, 2002

Construction and Screening of a Harudus obscurus Scorpion Genomic Library
Nicholas Adkins, Brandon Walker, Parthenia Cole, Victor Fet and Elizabeth Murray.

Incidence of 3 SNPs in West Virginia
Sarah Hesson, Poorani Sekar, Jean Chappell and Elizabeth Murray.

Evaluation of Strawberry as a Candidate Crop for Advanced Life Support.
Justin Hogan, Aaron Porter, Marcia Harrison, and Elizabeth Murray.

Screening a Tobacco Library for a candidate RIP gene
Kristen Winland and Elizabeth Murray

· Marshall University Sigma Xi Presentations with students: April 25-26, 2003

Homocysteine and MTHFR Genotype in and Obese West Virginia Population
Jooha Jeong, Jean Chappell, Mark Flood, Sarah Hesson, Brenda Hill, Jordan Nash, Jarrett Roth, Poorani Sekar, Gary Wright Mark Studney, Paulette Wehner, Elizabeth Murray and Bowie Kahle

Effects of Flooding on Ethylene Production in Strawberry Hydroponics
Justin Hogan, Matthew Taylor , Matthew Houdersheldt, Tim Lynch, Marcia Harrison, and Elizabeth Murray

Cardiovascular SNP Analysis in a West Virginia Sample
Sarah Hesson, Jean Chappell, Mark Flood, Brenda Hill, Jooha Jeong, Jordan Nash, Jarrett Roth, Poorani Sekar, Gary Wright and Elizabeth Murray.

Kraus, R.J., Murray, E.E., Wiley, S.R., Zink, N.M., Loritz, K., Gelembiuk, G.W. and Mertz, J.E.: Experimentally determined weight matrix definitions of the initiator and TBP binding site elements of promoters. Nuc. Acids Res. 24:1531-1539 (1996).

Hurst, R., Maffitt, M., Murray, E.E., Kappelman, J., Xu, Q., Mendez, J., Butler, B., Ryan, A., and Beckler, G.S. The TNTÒT7 Quick Coupled Transcription/Translation System. Promega Notes 58: 8-11 (1996).

Kappelman, J.R., Brady, M., Knoche, K., Murray, E., Schoenfeld, T., Williams, R., and Nadia Vesselinova SgfI, a new Type-II restriction endonuclease that recognizes the octanucleotide sequence 5’-GCGAT/CGC-3’ Gene 160: 55-58 (1995).

Wiley, S.R., Kraus, R.J., Zuo, F., Murray, E.E., Loritz, K., and Mertz, J.E.: SV40 early-to-late switch involves titration of cellular transcriptional repressors. Genes and Development 7: 2206-2219 (1993).

Degatayarev, S., Rechkunova, N., Zernovv, Y., Dedkov, V., Chizikov, V., Van Calligan, M., Williams, R., and Murray, E.E. Bsp24 I, A new, unusual restriction endonuclease. Gene 131: 93-95 (1993).

Murray, E.E., Firoozabady, E. and DeBoer, D.L.: Transgenic Cotton: in Kung, S. and Wu, R. (eds) Transgenic Plants, Volume 2 Present Status and Social and Economic Impacts; Academic Press, New York (1993)

Murray, E.E., Singer, K., Cash, K., and Williams, R. Cloning-qualified blunt end restriction enzymes: Causes and cures for light blue colonies. Promega Notes 41: 1-5.

Brewer, G. and Murray, E.E. RNase One: Advantages for nuclease protection assays. Promega Notes 36:1-7 (1992).

Murray, E.E., Lewis, K., Sobol, M., and Binghui, L. Optimizing and troubleshooting DNase I footprinting reactions. Promega Notes 36: 1-11 (1992).

Hung, L., Murray, E.E., Murray, W., Bandziulis, R., Lowry, R., and Nobel, R.A. Blue/White Cloning assay for quality control of DNA restriction and modifying enzymes. Promega Notes 33: 1-12. (1991).

Murray, E.E., Rocheleau, T.A., Eberle, M., Stock, C., Sekar, V., and Adang, M.: Analysis of unstable RNA transcripts of Insecticidal Crystal Protein Genes of Bacillus thuringiensis in transgenic plants and electroporated cells. Plant Mol. Biol. 16: 1035-1050 (1991).

Murray, E.E., Buchholz, W., and Bowen, B.: Direct analysis of RNA transcripts in electroporated carrot cells. Plant Cell Rep. 9: 129-132 (1990).

Murray, E.E., Lotzer, J. and Eberle, M.: Codon usage in plant genes. Nuc. Acids Res. 17: 477-498 (1989).

Adang, M.J., DeBoer, D., Endres, J., Firoozabady, E., Klein, J., Merlo, A., Merlo, D., Murray, E.E., Rashka, K., Stock, C.: Manipulation of Bacillus thuringiensis genes for pest insect control. In: Roberts, D.W. and Granados, R.R. (eds) Biotechnology biological pesticides and novel plant-pest resistance for insect pest management, Boyce Thompson Institute for Plant Research, Cornell University, Ithaca, NY (1989).

Firoozabady, E., DeBoer, D.L., Merlo, D.J., Halk, E.L., Amerson, L.A., Rashka, K.E., and Murray, E.E.: Transformation of cotton (Gossypium hirsutum L.) by Agrobacterium tumefaciens and regeneration of transgenic plants. Plant Mol. Biol. 10: 105-116 (1987).

Ladin, B.F., Murray, E.E., Halling, A.C., Halling, K.C., Tilakaratne, N., Long, G.L., Houston, L.L., and Weaver, R.F.: Characterization of a cDNA encoding ricin E, a hybrid ricin-Ricinus communis agglutinin gene from the castor plant, Ricinus communis. Plant Mol. Biol. 9:287-295 (1987).

Adang M.J., Firoozabady, E., Klein, J., DeBoer, D., Sekar, V., Kemp, J.D., Murray, E.E., Rocheleau, T.A., Rashka, K., Staffeld, G., Stock, C., Sutton, D., and Merlo, D.J.: Expression of a Bacillus thuringiensis insecticidal crystal protein gene in tobacco plants. In: Arntzen, C.J., and Ryan, C. (eds): Molecular Strategies in Plant Protection, pp. 345-353 (1987).

Murray, E.E.: Molecular Biology of the Ricin Multigene Family; Doctoral Dissertation, University of Kansas, Lawrence, Kansas (1986).

Halling, K.C., Halling, A.C., Murray, E.E., Ladin, B.F., Houston, L.L., and Weaver, R.F.: Genomic cloning and characterization of a ricin gene from Ricinus communis. Nuc. Acids Res. 13: 8019-8033 (1985).

Hedrick P. and Murray, E.E.: Selection and Measures of Fitness. In: Ashburner, M. and Novitski, E. (eds): The Genetics and Biology of Drosophila, Vol, IIIC, pp. 61-104 (1983).

Murray, E.E.: Twenty-first annual Drosophila conference report. Drosophila Information Service 55: 1-4 (1980).

Hedrick, P. and Murray, E.E.: Competition between D. melanogaster and D. simulans from natural populations. Drosophila Information Service 55: 58-59 (1980).

Hedrick, P. and Murray, E.E.: Average Heterozygosity Revisited. Amer. J. Hum. Genet. 30: 377-382 (1978).

Murray, E.E.: Numerical Taxonomy of the Primates based on Cytogenetics; Master’s Thesis, University of Missouri, Columbia, Missouri (1978).

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