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Faculty Profile

Name: Jagan Valluri
Title: Professor
Office: Biological Sciences/COS
Phone: 304-696-2409
Email: valluri@marshall.edu
Expert:
 
Achievements

Creative Works:
 
NASA, New Technology Award for Innovative Research. 2010.

NASA, Inventions and Contributions Award, Marshall Flight Center. 2008.

Planning Award U.S. Army Corps of Engineers, Environmental Planning Division, 1996.

Jessie Smith Noyes Foundation Fellowship Award, 1984.

Sigma Xi Research Award, 1983.
 
 
2011 – US 12339898: Methods for screening chemotherapeutic agents and treating cancer.

2010 – US 0062435A1: Methods for stem cell production and therapy.

2006 – US 0138828A: Microgravity bioreactor systems for production of bioactive compounds and biological macromolecules.
 

Research Based:
 
Publications:

Nande R, Di Benedetto A, Aimola PP, De Carlo1 F, Carper M, Claudio C, Denvir J, Valluri, JV, Duncan GC, Claudio PP, 2012. Targeting a Newly Established Spontaneous Feline Fibrosarcoma Cell Line by Gene Transfer. PLoS ONE 7(5): e37743. doi:10.1371/journal.pone.0037743

Mathis SE, Dougherty T, Kimmey GA, Neto W, Howard CM, Valluri JV, and Claudio PP, 2012. Clinical Cancer Research 2012 (In review). Chemosensitivity Screening on Cancer Stem-Like Cells and Bulk of Tumor Cells for a Case of Recurring Spinal Ependymoma.

Chemosensitivity Screening on Cancer Stem-Like Cells and Bulk of Tumor Cells for a Case of Recurring Spinal Ependymoma. Kelly SE, , Greco A, Howard CM, Sollars VE, Primerano DA, Valluri, JV, Claudio PP, 2010. Rapid Selection and Proliferation of CD133(+) Cells from Cancer Cell Lines: Chemotherapeutic Implications. PLoS ONE 5(4): e10035. doi:10.1371/journal.pone.0010035. 2010

Valluri, J.V., Bioreactor production of secondary metabolites from cell cultures of Periwinkle and Sandalwood. Protocols for in vitro cultures and secondary metabolite analysis of aromatic and medicinal plants. The Humana Press Inc., Springer, 2009, 325-335.

W. A. Kelly Jr., Kelly S. E., Valluri J. V., Effects of Simulated Microgravity on Growth and Metabolism of the Green Alga Chlorella Pyrenoidosa. European Space Agency Proceedings, SP – 663, 21-24, 2008.

S. E. Kelly, Di Benedetto A., Valluri, J.V., Claudio, P.P., Rapid Selection and Proliferation of Cancer Stem Cells in a NASA Developed Microgravity Bioreactor. European Space Agency Proceedings, SP – 663, 51-54, 2008.

W.A. Kelly Jr., S.E. Kelly, and J.V. Valluri. Protein expression in Glycine max cells under microgravity conditions. Gravitational and Space Biology Bulletin. Vol 21(1).12-13, 2007.

S.E. Kelly, P.P. Claudio, and J.V. Valluri. The effects of microgravity on stem cell differentiation. Gravitational and Space Biology Bulletin. Vol 21(1).18-19, 2007.

Valluri J.V., and S. Gonda. Anti-cancer alkaloids in a Hydrodynamic Focusing Bioreactor. NASA –Tech. Bulletin, Vol 20, 28-31, 2006

Ibrahim Sherrine, Deraimo David, Valluri, J.V., Regulation of gene expression in gravistimulated pea stems. A.S.B. Bulletin, Vol 48, No 2, pp 116-117, 2001.

Deraimo, D., Valluri J.V., "Characterization of molecular responses in gravistimulated pea stems". A.S.B. Bulletin 47:2, p 58, 2000.

Deraimo, D., Britt A, Valluri J.V., H.W. Elmore, "Protein synthesis and stress ethylene production in sandalwood callus cultures exposed to heat shock". A.S.B. Bulletin, Vol 46, No 2, pp 164-165, 1999.

Deraimo, D., Britt A, Valluri J.V., H.W. Elmore. "Protein synthesis and stress ethylene production in sandalwood callus cultures exposed to heat shock". A.S.B. Bulletin, Vol 46, No 2, pp 164-165, 1999.

Valluri, J.V, H.W. Elmore. "BandAnalyzer: software for the determination of protein Rf values and calculation of molecular weight". A.S.B. Bulletin 46:2, p124, 1999.

Holt, T., Valluri J.V., "Characterization of molecular responses in gravistimulated pea stems". A.S.B. Bulletin 46:2, p 58, 1999.
Valluri J.V., B.G. Cobb, R.J. Newton and E.J. Soltes. Changes in Protein and messenger RNA synthesis in slash pine hypocotyls upon pitch canker fungal infection. Journal of Phytopathology, 1999.

Deraimo D, A. Britt, J.V. Valluri, H.W. Elmore. Protein synthesis and stress ethylene production in sandalwood cultures exposed to heat shock. ASB Bulletin, Vol 44, No 2, pg 100, 1997.

Barnett J., J.V. Valluri, H. W. Elmore. Protein synthesis and ethylene biosynthesis in sandalwood callus cultures exposed to drought and heat shock. ASB Bulletin, Vol 44, No 2, pg 100, 1997.

Barnett J., J.V. Valluri, H. W. Elmore. Protein synthesis in sandalwood callus cultures. Proc.WV.Academy of Science, Vol 69, No 1, pg 5, 1997.

Barnett J., J.V. Valluri. Ethylene production in sandalwood callus cultures exposed to drought and heat shock. ASB Bulletin, Vol 43, No 2, pg 108, 1996.

Valluri J.V., R.J. Newton and B.G. Cobb. Synthesis of new host coded proteins in Pinus elliottii seedlings in response to pathogen and water stress. Journal of Phytopathology Vol 120 pp 235-244, 1995.

Valluri J.V. Santalum Album L. (Sandalwood): In Vitro Culture and the Bioreactor Production of Secondary Metabolites. Biotechnology, Vol 28, 401- 411,1994.

Valluri J.V., and D.B. Chambers. Protein synthesis in sandalwood callus cultures exposed to drought and salt stress. Plant Physiology and Biochemistry, Vol. 99, (5) 51 - 52, 1992.

Valluri J.V., W.J. Treat and E.J. Soltes. Bioreactor culture of heterotrophic sandalwood (santalum album L.) cell suspensions utilizing a cell-lift impeller. Plant Cell Reports, Vol 10: 366-370, 1991.

Valluri J.V. and E.J. Soltes. Callose formation during wound-inoculated reaction of Pinus elliottii to Fusarium Subglutinans. Phytochemistry, Vol 29 (1), 71-72, 1990.

Valluri J.V., W.J. Treat, J. Castillion and E.J. Soltes. Comparison of photomixotrophic and heterotrophiccallus and suspension cultures of Pinus elliottii: II. Water stress-induced changes in callus volume and protein profiles. Plant Physiology and Biochemistry, Vol 28, (1) 57-64, 1990.

W.M. Alexander and J.V. Valluri. Biofuel potential of Euphorbia Lathyris. Current Science Vol 4, 69-80, 1990.

Valluri J.V., J. Castillion, R.J. Newton and E.J. Soltes. Water stress induced changes in protein synthesis of Pinus elliottii hypocotyls. Journal of Plant Physiology, Vol 135, 355-360, 1989.
 
 
Technical Publications:

Valluri, J.V. Environmental Assessment, Grundy Flood Protection / Highway Upgrade Project, Grundy, Virginia, U.S. Army Corps of Engineers, 45 pages, 1999.

Valluri,J.V. Environmental Assessment, Section 14 Planning and Design Analysis for Streambank Protection, Lift Stations, and Sewer Line, South Charleston, WV, U.S. Army Corps of Engineers, 40 pages, 1998.

Valluri, J.V. (Co-author) Environmental Assessment, London Lock Expansion, U.S. Army Corps of Engineers, 60 pages, 1997.

Valluri, J.V. (Co-author) Environmental Assessment, Point Pleasant River Front Park Expansion, U.S. Army Corps of Engineers, 70 pages, 1996.

Valluri, J.V. (Co-author) Draft Environmental Impact Statement (FEIS), Spring Hills Subdivision, FmHA & U.S. Army Corps of Engineers, 60 pages, 1994.


Valluri, J.V. (Co-author) Environmental Impact Statement, Kanawha River Navigation Study, Marmet Lock Replacement, U.S. Army Corps of Engineers, 53 pages, 1993.

Valluri, J.V. (Co-author) Environmental Studies, Appendix C, Marmet Lock Replacement, U.S. Army Corps of Engineers, 130 pages,1993.

 

Professional/Community Based Service:
 
Meetings:

Presented paper titled"Personalized Chemotherapy Identified for a Case of Recurring Spinal Ependymoma" at the International Nanomedicine Conference, Delaware, August 16-18, 2012.

Presented paper titiled "ChemoID assay for personalized chemotherapy in solid tumors" at Saladax Corporation, Bethlehem, PA, June 29, 2012.

Attended NASA Space Biotechnology Conference, Johnson Space Center, Houston, April 14 -16, 2002.

Attended workshop on Fermentation Methods and Scale-Up Strategies, Penn State University, University Park, April 2-5, 2002.

Presented paper at the Association of Southern Biologists Conference titled “Regulation of gene expression in gravistimulated pea stems, Pisum sativum, Tulane University, New Orleans, April 5, 2001.

Attended Biotechnology and Bioprocess Engineering Conference organized by New Brunswick Scientific Company, New Jersey, March 6 - 8, 2002.

Valluri J.V. and S. Ibrahim. “Regulation of gene expression in gravistimulated pea stems, Pisum sativum, Tulane University, New Orleans, April 5, 2001.

Holt, T., Valluri J.V., "Characterization of molecular responses in gravistimulated pea stems". WV Academy of Science, April 10, 1999, Shepherd College, Shepherdstown, WV. (Received best paper award from an overall 26 papers)

J.V. Valluri, H.W. Elmore, "Bandanalyzer: software for determination of protein Rf values and calculation of molecular weight". A.S.B. (Association of Southeastern Biologists), April 15, 1999, The University of North Carolina, Wilmington.

Deraimo, D., Britt A, Valluri J.V., H.W. Elmore, "Protein synthesis and stress ethylene production in sandalwood callus cultures exposed to heat shock". WV Academy of Science, April 10, 1999, Shepherd College, Shepherdstown, WV. (Honorable mention - most outstanding paper)

Barnett, J., Valluri J.V., H.W.Elmore, "Protein synthesis and ethylene biosynthesis in sandalwood callus cultures exposed to drought and heat shock". A.S.B. (Association of Southeastern Biologists), April 18, 1997, Furman University, SC.

Barnett, J., Valluri J.V., "Protein synthesis in sandalwood callus cultures exposed to drought and heat shock. WV Academy of Science April 12, 1997, WV State College).

Barnett J., J.V. Valluri. Ethylene production in sandalwood callus cultures exposed to drought and heat shock. A.S.B. (Association of Southeastern Biologists), April 11, 1996, Georgia Southern University, Statesboro, Georgia.

 

Awards:
 
Research Grants

Title: Biofuels Production from Microalgae. Agency: NASA Amount $31,500. Effective dates: 7/1/09-6/30/10

Title: NASA Graduate Research Scholarship. Agency: NASA Amount: $24,000. Effective dates: 8/1/07-5/30/09

Title: Protein Production for Biological Support Systems. Agency: NASA Amount $30,000. Effective dates: 8/1/07-5/30/08

Title: NASA Graduate Research Scholarship. Agency: NASA Amount: $12,000. Effective dates: 8/1/07-5/30/08

Title: Production of Biomass and Protein for Advanced Life Support in a Microgravity-based Hydrodynamic Focusing Bioreactor (HFB). Agency: NASA Amount $25,000. Effective dates: 5/1/05-5/30/06.

Title: Characterization of HFB space bioreactor. Agency: USRA’s Division of Space Life Sciences. Amount $10,000. Effective dates: 10/2/04-3/15/05

Title: Plant Cell Culture Growth in a Microgravity-based Bioreactor. Agency: NASA Amount $25,000. Effective dates: 7/1/03-12/15/04

Title: Plant Cell Growth in HFB. Agency: USRA’s Division of Space Life Sciences. Amount $10,000. Effective dates: 9/2/02-3/15/03

Title: Environmental Impact Analysis, Belpre Riverfront Park. Agency: U.S. Army Corps of Engineers; Amount: $25,000, Effective Dates: 3/1/2002– 12/31/2002

Title: Bioreactor Production of Secondary Metabolites from Plant Cell Cultures
Agency: USDA-NRI; Amount: $25,000, Effective Dates: 10/1/2000 – 5/30/2001

Characterization of Hydrodynamic Focusing Bioreactor, Agency: NASA-USRA, Amount: $10,000, 2002.

Environmental Analysis for the Ohio River Main Stem, Agency: U.S. Army Corps of Engineers, Amount: $20,000, 2002

Bioreactor Production of Secondary Metabolites from Plant Cell Cultures, Agency: U.S. Dept of Agriculture, Amount: $25,000, 2001

Regulation of Gene Expression in Gravistimulated Pea Stems. Agency: NASA, Amount: $20,000, 2001

Development of Environmental Analysis and NEPA Reports for West Virginia, Agency: U.S. Army Corps of Engineers, Amount: $69,700, 2001.
 

Other Achievements:
 
Book Reviews:

Reviewed six chapters for Introduction to Biotechnology by Theiman and Palladino, Benjamin Cummings Publishers, 2003.

Reviewed three chapters titled "RNA Transcription /Processing, Protein Synthesis and Transcriptional /Translational Regulation for the new edition of Molecular and Cellular Biology by Stephen Wolfe. 2002

Reviewed four chapters for Biology 7th edition by Sylvia Mader, McGraw-Hill Publishers. 2001
 

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