Translational research aims to transfer discoveries from the laboratory to the bedside quickly
Wednesday, Feb. 27, 2013
HUNTINGTON, W.Va. – Marshall University Joan C. Edwards School of Medicine officials today announced $150,000 in funding for six research grants associated with the school’s translational medicine research program.
The Marshall Health Translational Pilot Grant program, created in 2012, encourages collaborative research between basic scientists and clinical physicians in an effort to speed up the process of laboratory discovery to clinical application for patients. The grants are funded by Marshall Health.
“We are very pleased that Marshall Health has created this grant program to stimulate research efforts,” said Richard M. Niles, Ph.D., senior associate dean for Biomedical Sciences at the School of Medicine. “Moving Marshall to the next level of medical research takes vision, commitment and of course, funding. This grant allows 12 researchers, as well as medical residents and students, the opportunity to explore very diverse areas.”
Marshall Health is the faculty practice plan for the Joan C. Edwards School of Medicine and supports the clinical, educational, research and services missions of the school. Beth Hammers, executive director of the organization, says the pilot grant program provides one year of support at $25,000 for each grantee, with additional funding based on progress of the research.
“Medical research is essential to the development of new medical treatments and cures for patients,” Hammers said. “We are thrilled to help stimulate a robust, viable grant program which pairs basic scientists from Marshall University with School of Medicine physicians to work on projects which will lead to the betterment of our community.”
The investigators and their projects are listed below:
Dr. Pier Paolo Claudio, Department of Biochemistry and Microbiology, and Dr. Anthony Alberico, Department of Neuroscience – “Chemotherapy resistance and sensitivity testing in tumors of the central nervous system”
Dr. Elaine Hardman, Department of Biochemistry and Microbiology, and Dr. James Jensen, Department of Surgery – “Feasibility and Safety of Nutritional Supplementation with Omega-3 Fatty Acids to Reduce Prostate Specific Antigen Rise in Men with Biochemical Failure after Prostatectomy or External-Beam Radiotherapy”
Dr. Nalini Santanam, Department of Pharmacology, Physiology and Toxicology, and Dr. Paulette Wehner, Department of Cardiology – “Perivascular Fat Relation to Hypertension—Appalachian Heart Study”
Dr. Nalini Santanam, Department of Pharmacology, Physiology and Toxicology, and Dr. Abid Yaqub, Department of Medicine, Endocrinology Section – “Impact of Technology-based Behavioral Intervention on Molecular and Clinical Parameters in Patients with Type 2 Diabetes”
Dr. Monica Valentovic, Department of Pharmacology, Physiology and Toxicology, and Dr. Brenda Dawley, Department of Obstetrics and Gynecology – “Prenatal Exposure to Heavy Metals and Polycyclic Aromatic Hydrocarbons (PAH) Alter Umbilical Cord Blood Levels of Thyroid Hormone and Vitamin D”
Dr. Hongwei Yu, Department of Biochemistry and Microbiology, and Dr. Yoram Elitser, Department of Pediatrics – “Investigate the distribution of segmented filamentous bacteria (SFB) in American children and the presence of SFB with childhood diseases”
Other current translational research under way at the Marshall University Joan C. Edwards School of Medicine includes a partnership with the University of Kentucky (UK) as part of the National Institutes of Health’s Clinical and Translational Science Awards program, which also is aimed at speeding the time for laboratory discoveries to benefit patients.
In 2011, UK and its partners received $20 million for the program to support research at UK’s Center for Clinical and Translational Science, making Marshall part of a select national biomedical research network.
Contact: Ginny Painter, Communications Director, Marshall University Research Corporation, 304.746.1964, or Leah C. Payne, Director of Public Affairs, Schools of Medicine and Pharmacy, 304-691-1713

On March 20th, the Marshall University School of Medicine hosted its 24th Annual Medical School Research Day. This medical-school wide event, which also encompasses the Biomedical Sciences Graduate Program, is one of the few times in the academic year that everyone in the school community gathers to learn about the research taking place at the Joan C. Edwards School of Medicine (JCESOM).
Dr. Philippe Georgel and Dr. W. Elaine Hardman have received considerable publicity in the past few years over their receipt of a grant from the Department of Defense’s Breast Cancer Research Program. Their most recent honor comes in being highlighted in the latest program book for the Congressionally Directed Medical Research Programs’ (CDMRP) Breast Cancer Research Program. Their research, the result of a DoD FY09 Idea Expansion award, is entitled “Maternal Consumption of Omega-3 Fatty Acids May Prevent Breast Cancer in Offspring.”
Miranda Carper will serve as the newly-elected President of the GSO. Miranda is a Ph.D. candidate as of November 2010 and is currently researching for the third year in Dr. Claudio’s lab. She is studying in the Cancer Biology Research Cluster within the Biochemistry/Microbiology Department. Miranda says that part of what attracted her to the Biomedical Sciences Program at Marshall University was the warm and welcoming nature of its students. After her second year in the program, she served as Secretary/Treasurer in order to become more involved with the GSO, as she feels it provides a great opportunity for students to collaborate in support of one another. Of her time in this position, she says that it “was a wonderful experience and allowed me to get my feet wet in the various things the GSO is involved in.” She decided to run for president this year with the goal of growing as an invidividual and as a leader. During her time as President, she hopes to live up to the example set by Aileen Marcelo and other predecessors by encouraging students to become more involved in improving the GSO and the Biomedical Sciences Graduate Program. In keeping with the GSO’s tradition of service, she also wants to hold a fundraiser to support those in need in Japan due to the earthquake and tsunami.
Allison Wolf, the GSO’s new Vice President, is a second year student and a Ph.D. student. She also researches in the Cancer Biology Cluster in Dr. Claudio’s lab. She applauds the GSO for helping to achieve many positive changes to the Biomedical Sciences Graduate Program within the past few years. She wanted to serve in this position, because its duties include serving as a liaison between the faculty and students. She feels that this bridge provides one of the best opportunities available for students to help the program be the best it can be. Of her election to the post, Allison says, “I am really proud to be a member of this organization. Apart from keeping the interests of the students addressed, we really do have a strong volunteer aspect to our organization.” During her year of service, she hopes to help improve the website as a resource for students searching for funding opportunities, to aid in guiding new and incoming students, and to encourage students to give voice to their concerns and ideas for the program.
Rounding out the list of new officers is Johannes Fahrmann, the new Secretary/Treasurer for the GSO. Johannes is a Ph.D. student in Biochemistry and researches in the Cancer Biology Cluster with an emphasis on Nutrition and Cancer. He researches in Dr. W. Elaine Hardman’s lab. Johannes sought the position to become more involved with the organization and to help give back to the Biomedical Sciences Graduate Program and its future students. He feels that the GSO is doing an excellent job in its service to the program and hopes to fulfill the functions of the position to his utmost ability. Of his goals for his new position, he says, “I would like to target fundraising by improving or introducing new novel fundraising events so that the organization may be able to expand its capabilities and related events.”
Dr. Elaine Hardman of the Biomedical Sciences Program has been featured by MU-Advance, an organization on campus that seeks to empower, retain, and recruit female faculty members in the fields of science, technology, engineering, and mathematics (STEM). The following is the piece the MU-Advance ran on Dr. Hardman:
Congratulations to Gary O. Rankin, Ph.D. and his WV-INBRE team for receiving the National Institutes of Health (NIH) competitive renewal grant of 17.8 million dollars! The grant will be for five years and will help continue a multidisciplinary research network with a scientific focus that will build and strengthen the lead and partner institutions (primarily undergraduate institutions) across West Virginia. “(This money) establishes research in colleges and universities around this state where research was never happening,” Dr. Rankin said. “It will lead to more dollars going to these universities, which will create new jobs.”