Updated10/31/97
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- CMS Molecular Biology Resource Page
- Christopher M. Smith, Department of Biochemistry, Univ. of Nebraska -Lincoln, "maintains this compendium of electronic and Internet-accessible tools and resources for Molecular Biology, Biotechnology, Molecular Evolution, Biochemistry, and Biomolecular Modeling." New in January 1996.
- Glossary of Biochemistry and Molecular Biology
- short definitions, but fairly comprehensive.
- Primer on Molecular Genetics
- This is an authoritative resource for those who want to familiarize themselves with the terminology, research techniques, and implications of molecular genetic research. It was written for the 1991-92 DOE Human Genome Program Report, which is a bit of disadvantage in this rapidly moving field. An extensive revised edition is promised by Human Genome Management Information System.
- Kimball's Biology Pages
- are not strictly molecular genetics, but are a general biology resource that is produced by the author (Dr. John W. Kimball)
of standard biology textbooks. It works like a thesaurus which connects to numerous detailed discussions and illustrations.
- Human Genome Project Information
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Explore this site for material about the history, progress, research, and resources of the Human Genome Project. From the the Human Genome Management Information System (HGMIS) for the U.S. Department of Energy's Human Genome Program.
- Hopkins Bio-Informatics Home Page
- has links to many sequencing databases including Prot-Web, which "is a Collection of Protein Databases which contain links to one another as well as links to other databases around the world" and "OWL - a non-redundant protein sequence database which ties a number of databases together."
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Human Genome Center at Lawrence Berkeley Laboratory
- The National Center for Biotechnology Information
- "is responsible for building, maintaining, and distributing GenBank , the NIH genetic sequence database that collects all known DNA sequences from scientists worldwide. . . There are approximately 318,000,000 bases and 415,000 sequences as of June 1995. . . . a new release is made every two months." See the GenBank Overview Article or A five-page description for more information.
- Searching GenBank Files
- Entrez Browser for Medline Subset
searches the genetics subset of Medline. There is no charge and the searching interface is effective, allowing for field searches on MESH headings. Beware, this is the so-called free Medline search that is often mentioned on the Net, but many Web surfers don't realize that it's only a special subset, which is only 18% of 8 million records in the complete Medline database.
- BankIt -- GenBank Submissions by WWW allows researchers to report sequencing data to Genebank, which is often required by journals before research can be published.
- Online Mendelian Inheritance in Man (OMIM)
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"is a catalog of human genes
and genetic disorders authored and edited by Dr. Victor A. McKusick and colleagues at Johns Hopkins and elsewhere, and developed for the World Wide Web by NCBI . . . The database contains textual information, pictures, and reference information. It also contains
copious links to NCBI's Entrez database of MEDLINE articles and sequence information. "
Go directly to OMIN Search
- Gene Map of the Human Genome - RNA Transcript Map
- appears on the NCBI site and in the October 25, 1997 issue of Science. You can break out a specific sequence within a gene on the Web site and retrieve citations from Genebank databases.
The maps brings together the work of eight institutions:
to create the most comprehensive gene map to date (10/25/96), which includes 16K of the estimated 50K-100K genes of the human genome. You can browse
by chromosome or the featured disease-causing genes.
See the accompanying Science article that explains how the map was constructed and its uses.
- Human Genome Map
- covers about 95% of the genome. Provided by the Whitehead Institute for Biomedical Research
, "this is a composite map in which the genetic linkage map from Généthon , and the radiation hybrid map from the Whitehead Institute/MIT Center are used to anchor YAC/STS contigs. We only show the subset of genetic- and radiation-hybrid mapped STSs for which positive YACs are present. For the genetic map, please refer to the linkage maps published in Nature Genetics
7(2):246-339 (1994)." See the Dec 22nd 1995 issue of Science 270(5244):1919-20 for further explaination.
- Plant and Animal Genomic Information
- has many large databases on agriculturally significant plant and animal genomes. Many clever acess points enable users to quickly find what they need. Provided by US Department of Agriculture.
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Sequencing data from Baylor
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Cold Spring Harbor
- TIGR, The Institute for Genomic Research
- "is a not-for-profit research institute with interests in structural, functional,
and comparative analysis of genomes and gene products in viruses, eubacteria, pathogenic bacteria, archaea, and eukaryotes, both plant and animal, including humans. . ."
Some Databases require registration by user or their institutions, while others are open to searching by all Web users.
Return to Molecular Genetics Section on the Health Page
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