The scientific vision of the proposed West Virginia Network for Functional Neuroscience and Transcriptomics (WV-NFNT) is to transform neuroscience research in West Virginia (WV) by establishing connections and enabling access to the technologies and expertise needed for high resolution structure-function studies.\u00a0 This will contribute to one of the most impactful neuroscience research areas \u2013 circuit and synaptic plasticity. We will build capacity by making strategic faculty and staff hires, adding state-of the art microscopy and spatial transcriptomics infrastructure, and facilitating growth of the neuroscience community across the state. We will expand the capability and diversity of those working in the fields of neuroscience and bioinformatics through support for faculty, post docs, educators, and students, and by implementing specific education and workforce development activities to engage underrepresented students, especially rural, first-generation college students, in these research areas.<\/p>\n