NIH General Application Guide (G.120) Significant Changes | December 2025 May 14, 2026 Share NIH released significant updates to the General Application Guide for NIH and other PHS agencies. NIH G.120 Significant Changes Recent Releases Federal Update: DOE eXCHANGE Systems Moving to Consolidated Site October 1, 2026 NASA Research Security Training Requirement Effective August 5, 2026 June 9, 2026 Implementing SimplerNOFO at NIH: A Clearer, Simpler Path for Applicants May 28, 2026