Colloquium: “Genetic analyses of late-onset Alzheimer’s Disease”

Marshall University Math Colloquium
March 8, 2016

Shubhabrata (Joey) Mukherjee
University of Washington, Seattle

Alzheimer’s disease is the most common form of dementia. Genetics of late-onset Alzheimer’s disease (LOAD) is very complex. Genome-wide Association Studies (GWAS) are an important first step. Gene-based and network/pathways based analyses also contribute to the understanding of genetic determinants of LOAD. Thus, a three-component approach — GWAS, gene-based, and network-based analyses — is likely to best illuminate genetic determinants of a disease. I will explore the three component approach in this talk.